I enjoy producing under the influence, but I make sure to keep myself at a good buzz.
Weed: It definitely helps all of us hear better and it can give you a very fresh perspective on your project, as if you havent heard it for weeks sometimes. Or, if you're creating something new, it gets the creative juices flowing nicely but you have to catch yourself when you get too obsessed over one small detail, which I tend to do when I've been going at it for more than 30-45 minutes. Some of my best ideas have come to me while high, BUT you have to make sure you dont RELY ON IT to where you can only be creative when you smoke. Producing sober has great advantages.
Shrooms: I had a good time producing while tripping. No, you dont see unicorns or anything. It simply gives you another perspective.
Alcohol: I like to make a strong mixed drink when I sit down to produce sometimes (just one). It relieves the tension in my body and mind and allows things to flow more freely (as with the other substances I mentioned)
Coffee: It's a stimulant and calling it a drug implies that it harms your body like the other drugs. I enjoy 2 cups of coffee a day and it really picks me up and gets my brain parts working well.
Adderall: You will be extremely productive but Adderall has really bad side effects for long term use. Say goodbye to your eyesight among other things and it makes your concentration worse when you're not on it. ADHD is a funny thing because you can overcome it and its not something that you need pills for. Just meditate.
Showering : Not a drug but it stimulates the creative parts of your brain and if you have ever noticed that you feel creative after getting out the shower, now you know why.
So I'll take a shower, make some coffee, take a couple hits from the peace pipe, and let my imagination take over