I'm pretty positive Skrillex does his mixdowns on Beats by Dre, obviously we're not all Skrillex but as long as you're used to the headphones you're mixing with then you should be able to compensate. I'm a firm believer of constantly referencing your mixdowns with well produced songs (my FL studio template is literally just "Flicker" by Porter Robinson to use as a reference track, lol), which will keep your ears in check regardless of what headphones you use.