Something to remember about this big room/main room electro house style is the importance of layering. There are three main layers in your typical  THREE TWO ONE JUMP drop lead:

1. Supersaw layer of varying degrees of detuned-ness.

2. A clean saw wave to add clarity and punch, or another supersaw of different detunedness and/or in a different octave.

3. White noise or bright noise.

From there, mess with reverb, OTT compression, distortion/saturation, and see what you can get. If you can't get it in one patch, don't worry - most of these guys are layering more than one synth on top of each other. If you're really stuck, just flick through lead presets until you find ones that fit these three characteristics (that's probably how a lot of these guys work), play them on top of one another, then see what each one does to contribute to the overall sound!

its down to the sound design technique of the producer, you cant always get sound 100% close to it, but you can get close

if you look at the MainStage stuff, W&W use a lot of sylenth and massive, to get their dutch sounds
remmeber sylenth is a dutch analogue synth and massive is Wavetable

its best you study synthesis and sound design, so you can train your ears when you hear a sound, you know the workings of it and can replicate it in a way, the horn was from sylenth and saw from massive